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Rai, A.; Liu, T.; Katrukha, E.A.; Estévez-Gallego, J.; Manka, S.W.; Paterson, I; Díaz, J.F.; Kapitein, L.C.; Moores, C.; Akhmanova, A.
[2021]. Lattice defects induced by microtubule stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes PNAS (2021) 118 (51) e2112261118
Gallego-Páramo, C.; Hernández-Ortiz, N.; Buey, R.M.; Rico-Lastres, P.; García, G.; Díaz, J.F.; García, P.; Menéndez, M.
[2021]. Structural and functional insights into Skl and Pal endolysins, two cysteine-amidases with antipneumococcal activity. Frontiers in Microbiology (2021) 12, 740914. https://doi.org/10.3389/fmicb.2021.740914
Thakkar, P.V.; Kita, K.; del Castillo, U.; Galletti, G.; Madhukar; N.; Vila-Navarro, E.; Barasoain, I.; Goodson, H.V.; Sackett, D.; Díaz, J.F.; Lu, Y; RoyChoudhary, A.; Molina, H.; Elemento, O.; Shah, M.A.; Giannakakou, P.
[2021]. CLIP-170S is a novel microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement. Developmental Cell. (2021) Vol.56(23), p.3264-3275.e7 https://doi.org/10.1016/j.devcel.2021.09.023
Bold, C.; Klaus, C.; Pfeiffer, B.; Schürmann, J.; Lombardi, R.; Lucena-Agell, D.; Díaz, J.F.; Altmann, K.-H.
. Studies Towards the Synthesis of an Oxazole-Based Analog of (‒)-Zampanolide Org. Letters (2021) 23, 6, 2238–2242 https://dx.doi.org/10.1021/acs.orglett.1c00378
Guerra, W.D.; Lucena-Agell, D.; Hortigüela, R.; Rossi, R.A.; Díaz, J.F.; Padrón, J.M. and Barolo, S.M.
[2021]. Design, Synthesis, and In Vitro Evaluation of Tubulin-targeting Dibenzothiazines with Antiproliferative Activity as Novel Heterocycle Building Block. ChemMedChem (2021) 16, 3003–3016 https://doi.org/10.1002/cmdc.202100383
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[2021]. Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. PNAS (2021) Vol. 118 No. 9 e2021847118 https://doi.org/10.1073/pnas.2021847118
González, Myriam, Alcolea, Pedro José, Álvarez, Raquel, Medarde, Manuel, Larraga, Vicente, Peláez, Rafael
[2021]. New diarylsulfonamide inhibitors of Leishmania infantum amastigotes” International Journal for Parasitology: Drugs and Drug Resistance. (2021) 16, 45-6416:45-64.
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[2020]. Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and downregulation of c-Myc Medicinal Chemistry, (2020) 16, 1-11 https://doi.org/10.2174/1573406416666201120103913
Peronne, L; Denarier, E.; Rai, A.; Prudent, R.; Vernet, A.; Suzanne, P.; Ramirez-Rios, S.; Michallet, S.; Guidetti, M.; Vollaire, J.; Lucena-Agell, D.; Ribba, A.S.; Josserand, V.; Coll, J.L.; Dallemagne, P.; Díaz, J.F.; Oliva, M.A.; Sadoul, K.; Akhmanova, A.; Andrieux, A.; Lafanechère, L.
[2020]. Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells. Cancers 12, 2196
Oliva, M.A.; Prota, A.E.; Rodríguez-Salarichs, J.; Gu, W.; Bennani, Y.L.; Jiménez-Barbero, J.; Bargsten, K.; Canales, A.; Steinmetz, M.O.; Díaz, J.F.
[2020]. Structural basis of noscapine activation for tubulin binding J. Med. Chem 63, 15, 8495–8501
Keenan, B., Finol‑Urdaneta, R.K.; Hope, A.; Bremner, J.B.; Kavallaris, M., Lucena‑Agell, D.; Oliva, M.A.; Díaz, J.F.; Vine, K.L.
[2020]. N‑alkylisatin‑based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity Cancer Cell Int 20:170
Estévez-Gallego, J.; Josa-Prado, F.; Ku, S.; Buey, R.M.; Balaguer, F.A., Prota, A.E.; Lucena-Agell, D.; Kamma-Lorger,C.; Steinmetz, M.O.; Barasoain,I.; Chrétien, D.; Kamimura, S.; Díaz, J.F.; Oliva, M.A.
[2020]. Structural model for differential cap maturation at growing microtubule ends (2020) eLife 2020, 9, e50155
Torres, M.D.; Flórez-Fernández, N.; Simón-Vázquez, R.; Giménez-Abián, J.F.; Díaz, J.F.; González-Fernández, A.; Domínguez, H.
[2020]. Fucoidans: The importance of processing on their anti-tumoral properties. Algal Research 45, 101748
Bonandi, E.; Foschi, F.; Dapiaggi, F.; Sironi, M.; Pieraccini, S.; Christodoulou, M.S.; Balaguer, F.A.; Díaz, J.F.; Zidar, N.; Passarella, D.
[2019]. Synthesis of thicolchicine-based conjugates: investigation towards bivalent tubulin/microtubules binders ChemPlusChem 84, 98–102
La Sala, G., Olieric,N.; Sharma, A.; Viti, F.; Balaguer Perez, F.A.;Huang, L; Tonra, J.R.; Lloyd, G.K.; Decherchi, S.; Díaz, J.F.; Steinmetz, M.O.; Cavalli, A.
[2019]. Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes Chem 5,11, 2969-2986
Brindisi, M.; Ulivieri, C.; Alfano, G.; Gemma, S.; Balaguer, F.A.; Khan, T.; Grillo, A.; Chemi, G.; Menchon, G.; Prota, A.E.; Olieric, N.; Lucena-Agell, D.; Barasoain, I.; Diaz, J.F.; Nebbioso, A.; Conte, M.R.; Lopresti, L.; Magnano, S.; Amet, R.; Kinsella,P.; Zisterer, D.M.; Ibrahim, O.; O'Sullivan, J.; Morbidelli,L.; Spaccapelo, R.; Baldari, C.; Butini, S.; Novellino,E.; Campiani, G.; Altucci, L.; Steinmetz, M.O.; Brogi S.
[2019]. Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents European Journal of Medicinal Chemistry 162 290-320
