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  2. The role of mitochondria-associated ER membranes (MAM) in cellular homeostasis
  3. Publications

Planas-Serra L, Launay N, Goicoechea L, Heron B, Jou C, Juliá-Palacios N, Ruiz M, Fourcade S, Casasnovas C, De La Torre C, Gelot A, Marsal M, Loza-Alvarez P, García-Cazorla À, Fatemi A, Ferrer I, Portero-Otin M, Area-Gómez E, Pujol A.  [2023]. Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity. J Clin Invest. 2023 Mar 23;e162957. doi: 10.1172/JCI162957. Online ahead of print. PMID: 36951944

Agrawal RR, Larrea D, Xu Y, Shi L, Zirpoli H, Cummins LG, Emmanuele V, Song D, Yun TD, Macaluso FP, Min W, Kernie SG, Deckelbaum RJ, Area-Gomez E.  [2022]. Alzheimer’s-associated upregulation od mitochondria-associated ER membranes after traumatic brain injury. Cell Mol Neurobiol. 2022 Dec 26. doi: 10.1007/s10571-022-01299-0. Online ahead of print. PMID: 36571634

Avisar H, Guardia-Laguarta C, Surface M, Papagiannakis N, Maniati M, Antonellou R, Papadimitriou D, Koros C, Athanassiadou A, Przedborski S, Lerner B, Stefanis L, Area-Gomez E.  [2022]. Lipid level alteration in human and cellu.ar models of alpha synuclein mutations. NPJ Parkinsons Dis. 2022 Apr 25;8(1):52. doi: 10.1038/s41531-022-00313-y. PMID: 35468903. PMID: 35468903.

Miranda AM, Ashok A, Chan RB, Zhou B, Xu Y, McIntire LB, Area-Gomez E, Di Paolo G, Duff KE, Oliveira TG, Nuriel T.  [2022]. Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice. Transl Psychiatry. 2022 Mar 29;12(1):129. doi: 10.1038/s41398-022-01881-6. PMCID: PMC8964762. PMID: 35351864.

Çoku J, Booth DM, Skoda J, Pedrotty MC, Vogel J, Liu K, Vu A, Carpenter EL, Ye JC, Chen MA, Dunbar P, Scadden E, Yun TD, Nakamaru-Ogiso E, Area-Gomez E, Li Y, Goldsmith KC, Reynolds CP, Hajnoczky G, Hogarty MD.  [2022]. Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance. EMBO J. 2022 Apr 19;41(8):e108272. doi: 10.15252/embj.2021108272. Epub 2022 Feb 25. PMCID: PMC9016347. PMID: 35211994.

Avisar H, Guardia-Laguarta C, Area-Gomez E, Surface M, Chan AK, Alcalay RN, Lerner B.  [2021]. Lipidomics Prediction of Parkinson's Disease Severity: A Machine- Learning Analysis. J Parkinsons Dis. 2021;11(3):1141-1155. doi: 10.3233/JPD-202476. PMID: 33814463; PMCID: PMC8355022.

Urso A., Leiva-Juárez M.M., Briganti D.F., Aramini B., Benvenuto L., Costa J., Nandakumar R., Area Gomez E., Robbins H.Y., Shah L., Aversa H., Sonnet J.R., Arcasoy S., Cremers S., D'Ovidio F.  [2021]. Aspiration of conjugated biles acids predicts adverse lung transplant outcomes and correlates with airway lipid and cytokine dysregulation. J. Heart and Lung transp. 2021 Sep;40(9):998-1008. doi: 10.1016/j.healun.2021.05.007. PMID: 34183226

Ibáñez F, Montesinos J, Area-Gomez E, Guerri C, Pascual M.  [2021]. Ethanol Induces Extracellular Vesicle Secretion by Altering Lipid Metabolism through the Mitochondria-Associated ER Membranes and Sphingomyelinases. Int J Mol Sci. 2021 Aug 5;22(16):8438. doi: 10.3390/ijms22168438. PMCID: PMC8395151. PMID: 34445139.

Area-Gomez E*, Larrea D, Yun T, Xu Y, Hupf J, Zandkarimi F, Chan RB, Mitsumoto H.  [2021]. Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders. Sci Rep. 2021 Jun 30;11(1):13562. doi: 10.1038/s41598-021-92112-3. PMCID: PMC8245424. PMID: 34193885.

Sol J, Jové M, Povedano M, Sproviero W, Domínguez R, Piñol-Ripoll G, Romero- Guevara R, Hye A, Al-Chalabi A, Torres P, Andres-Benito P, Area-Gómez E, Pamplona R, Ferrer I, Ayala V, Portero-Otín M.  [2021]. Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression. Brain Commun. 2021 Jun 26;3(3):fcab143. doi: 10.1093/braincomms/fcab143. eCollection 2021. PMCID: PMC8361390. PMID: 34396104.

Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z.  [2020]. Ribosome-associated vesicles. A dynamic compartment of the ER in secretory cells. Sci Adv. 2020 Apr 1;6(14):eaay9572. doi: 10.1126/sciadv.aay9572. eCollection 2020 Apr. PMCID: PMC7112762. PMID: 32270040

Ozdinler PH, Gautam M, Gozutok O, Konrad C, Manfredi G, Area Gomez E, Mitsumoto H, Erb ML, Tian Z, Haase G.  [2020]. Better understanding the neurobiology of primary lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Nov;21(sup1):35-46. doi: 10.1080/21678421.2020.1837175. PMCID: PMC8016556. PMID: 3360201.

Agrawal RR, Montesinos J, Larrea D, Area-Gomez E, Pera M  [2020]. The silence of the fats. Neurobiol Dis. 2020 Nov;145:105062. doi: 10.1016/j.nbd.2020.105062. Epub 2020 Aug 29. PMID: 32866617

Pascual-Caro C, Orantos-Aguilera Y, Sanchez-Lopez I, de Juan-Sanz J, Parys JB, Area-Gomez E, Pozo-Guisado E, Martin-Romero FJ.  [2020]. STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells. Int J Mol Sci. 2020 Sep 9;21(18):6598. doi: 10.3390/ijms21186598. PMCID: PMC7555297. PMID: 32916960.

Montesinos J. Pera M. Larrea D., Guardia-Laguarta C, Agrawal R.R., Velasco KR, Yun D., Stavrovskaya I, XU Y., Koo Y., Snead AM., Sproul AA., Area-Gomez E.  [2020]. The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking EMBO J. 2020 Oct 15;39(20):e103791. doi: 10.15252/embj.2019103791. Epub 2020 Aug 31. PMCID: PMC7560219. PMID 32865299

Pera M, Montesinos J, Larrea D, Agrawal RR, Velasco KR, Stavrovskaya IG, Yun TD, Area-Gomez E  [2020]. MAM and C99, key players in the pathogenesis of Alzheimer's disease. (2020). Int Rev Neurobiol. 2020;154:235-278. doi: 10.1016/bs.irn.2020.03.016. Epub 2020 Jul 22. PMID: 32739006.

Area-Gomez, E*., Larrea, D., Guilfoyle. D.N., Pirhaji. L., Agrawal R.R., Shannon. K, Arain. H., Ashok. A., Pera. M., Chen Q., Dillman. A.A., Figueroa. H., Cookson M.R., Gross S.S., Fraenkel E., Duff. K.E, Nuriel. T.  [2020]. APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice. Scientific reports. 2020 Mar 9;10(1):4277. doi: 10.1038/s41598-020-61142-8. PMCID: PMC7062695. PMID: 32152337.

Montesinos J, Guardia-Laguarta C, Area-Gomez E  [2020]. The Fat Brain. Curr Opin Clin Nutr Metab Care . 2020 Mar;23(2):68-75. doi: 10.1097/MCO.0000000000000634. PMID: 32004239.

Agudelo CW, Kumley BK, Area-Gomez E, Xu Y, Dabo AJ, Geraghty P, Campos M, Foronjy R, Garcia-Arcos I.  [2020]. Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD). PLoS One. 2020 Feb 6;15(2):e0228279. doi: 10.1371/journal.pone.0228279. eCollection 2020. PMCID: PMC7004328. PMID: 32027677.

Montesinos J, Area-Gomez E, Schlame M  [2020]. Analysis of phospholipid synthesis in mitochondria. Methods Cell Biol. 2020;155:321-335. doi: 10.1016/bs.mcb.2019.12.003. Epub 2020 Jan 9. PMID: 32183965.

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