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Bohnacker, T.; Prota, A.; Beaufils, F.; Burke, J.; Melone, A.; Inglis, A.; Rageot, D.; Sele, A.; Cmiljanovic, V; Cmiljanovic, N.; Bargsten, K.; Aher, A.; Akhmanova, A. Diaz, J.F.; Fabbro, D.; Zvelebil, M.; Williams, R.; Steinmetz, M.; and Wymann; M.
[2017]. Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nature Communications. Article number:14683
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[2017]. Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin. Cell Chemical Biology, 24 (6), 737-750
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[2017]. Structural Basis of Microtubule Stabilization by Discodermolide. ChemBioChem 18, 905-909
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[2016]. Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells. ACS Omega. 1 (6), 1192-1204
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[2016]. Increased abundance of proteins involved in resistance to oxidative and nitrosative stress at the last stages of growth and development of Leishmania amazonensis promastigotes revealed by proteome analysis.
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[2016]. Differential protein abundance in promastigotes of nitric oxide-sensitive and resistant Leishmania chagasi strains.
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[2016]. In vitro infectivity and differential gene expression of Leishmania infantum metacyclic promastigotes: negative selection with peanut agglutinin in culture versus isolation from the stomodeal valve of Phlebotomus perniciosus.
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[2016]. Influence of the microenvironment in the transcriptome of Leishmania infantum promastigotes: sand fly versus culture.
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[2016]. A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage.
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[2016]. Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin J. Nat. Prod., 79 (8), pp 2113–212.
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[2016]. Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) Molecules 21, 1010
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[2016]. Synthesis and Anti-Proliferative Activity of Sulfanyltriazolyl 3-Naphthalenols and Naphthalene-1,4-diones. Arch. Pharm. Chem. Life Sci. 2016, 349, 9, 749-761
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[2016]. Aggregated compound biological signatures facilitate phenotypic drug discovery and target elucidation (2016) ACS Chem. Biol. 11, 3024-3034
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[2016]. Proteome profiling of the growth phases of Leishmania pifanoi promastigotes in axenic culture reveals differential abundance of immunostimulatory proteins.
