Ruiz FM, Huecas A, Santos-Aledo A, Prim EA, Andreu JM*, Fernandez-Tornero C*. PLoS Biol 20(3):e3001497. doi: 10.1371/journal.pbio.3001497
[2022]. FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics
Huecas S, Araujo-Bazan L, Ruiz FM, Ruiz-Avila LB, Martinez RF, Escobar-Peña A, Artola M, Vazquez-Villa H, Martin-Fontecha M, Fernandez-Tornero C*, Lopez-Rodriguez ML*, Andreu JM* (2021)
. Targeting the FtsZ allosteric binding site with a novel fluorescence polarization screen, cytological and structural approaches for antibacterial discovery. J. Med, Chem, 64, 5730-5745. doi: 10.1021/acs.jmedchem.0c02207
Huecas S, Canosa-Valls AJ, Araújo-Bazán L, Ruíz FM, Laurents DV, Fernandez-Tornero C*, Andreu JM* (2020)
. Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. FEBS J, doi:10.1111/febs.15235
Araújo-Bazán L, Huecas S, Valle J, Andreu D, Andreu JM
[2019]. Synthetic developmental regulator MciZ targets FtsZ across Bacillus species and inhibits bacterial division. Molecular Microbiology, 111, 865-980 & cover. doi: 10.1111/mmi.14198
Huecas S, Ramirez-Aportela E, Vergoñós A, Nuñez-Ramirez R, Llorca O, Diaz JF, Juan-Rodriguez D, Oliva M.A., Castellen P, Andreu JM.
[2017]. Self-organization of FtsZ polymers in solution reveals spacer role of the disordered C-terminal tail. Biophysical J., 113, 1831-1844 & cover. doi: 10.1016/j.bpj.2017.08.046
Field J, Pera B, Estévez-Gallego J, Calvo E, Rodríguez-Salarichs J, Sáez-Calvo G, Zuwerra D, Jordi M, Andreu JM, Prota A, Menchon G, Altmann K-H, Díaz JF
[2018]. Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites: J. Nat. Prod. 81, 494-505. doi: 10.1021/acs.jnatprod.7b00704
Wagstaff J, Tsim M, Oliva MA, García-Sanchez A, Kureisaite-Ciziene D, Andreu JM, Löwe J
[2017]. A polymerisation-associated conformational switch in FtsZ that enables treadmilling. Mbio, 8, e00254-17. doi: 10.1128/mBio.00254-17
Saez-Calvo G, Sharm A, Balaguer FA, Barasoain I, Rodríguez‐Salarichs J, Muñoz-Hernadez H, Berbis MA, Wendeborn S, Peñalva MA, Matesanz R, Canales A, Prota AE, Jimenez-Barbero J, Andreu JM, Lamberth C, Steinmetz M, Diaz JF
[2017]. Triazolopyrimidines stabilize microtubules by binding to the vinca inhibitor site of tubulin. Cell Chemical Biology, 24, 737-750. DOI: 10.1016/j.chembiol.2017.05.016
Jornet D, Boscá F, Andreu JM, Tormos R, Miranda MA
[2016]. Analysis of mebendazole binding to its target biomolecule by laser flash photolysis. J. Photochem. Photobiol. B 155, 1-6. doi:10.1016/j.jphotobiol.2015.12.003
Boscá F, Sastre G, Andreu JM, Jornet D, Tormos R, Miranda MA 2015
[2015]. Drug-tubulin interactions interrogated by transient absorption spectroscopy (2015) RSC Advances 5, 49451-49458. DOI: 10.1039/c5ra05636e
Oliva MA, Andreu JM
[2014]. Tub and FtsZ superfamily of protein assembly machines (review) In: eLS, Encyclopedia of Life Sciences (e-Book chapter; John Wiley & Sons, Ltd. Chichester) doi: 10.1002/9780470015902.a0025586
Canales A, Nieto L, Rodríguez-Salarichs J, Sánchez-Murcia PA, Coderch C, Cortés-Cabrera A, Paterson I, Carlomagno T, Gago F, Andreu JM, Altmann KH, Jiménez-Barbero J, Díaz JF
[2014]. Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches. ACS Chem Biol 9, 1033−1043 dx.doi.org/10.1021/cb400673h
den Blaauwen T, Andreu JM, Monasterio O
[2014]. Bacterial cell division proteins as antibiotic targets (review) Bioorganic Chemistry 55, 27–38. doi:10.1016/j.bioorg.2014.03.007
Martínez-Díez M, Guillén-Navarro MJ, Pera B, Bouchet BP, Martínez-Leal JF, Barasoain I, Cuevas C, Andreu JM, García-Fernández LF, Díaz JF, Avilés P, Galmarini CM
[2014]. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors. Biochem Pharmacol, 88, 291–302. doi: 10.1016/j.bcp.2014.01.026
