Description
We use MEL (murine erythroleukemia) cells as a model system to identify genes involved in cell differentiation. MEL cells derive from erythroid precursors that have their differentiation pathway blocked. They can be induced to re-initiate differentiation by a number of treatments including hexamethylenbisacetamide (HMBA). Our main goal is to identify genes that are activated or repressed during the early steps of differentiation. To know more about our latter achievements in this field click here.
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