Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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Alcolea, P.J., Alonso, A., García-Tabares, F., Ciordia, S., Mena, M.C., Larraga V. [2016]. Increased abundance of proteins involved in resistance to oxidative and nitrosative stress at the last stages of growth and development of Leishmania amazonensis promastigotes revealed by proteome analysis.

Alcolea, P.J., Tuñón, G.I.L., Alonso, A., García-Tabares, F., Ciordia, S., Mena, M.C., Campos, R.N.S., Almeida R.P., Larraga, V. [2016]. Differential protein abundance in promastigotes of nitric oxide-sensitive and resistant Leishmania chagasi strains.

Alcolea, P.J., Alonso, A., Larraga, V. [2016]. Rationale for selection of developmentally regulated genes as vaccine candidates against Leishmania infantum infection. Vaccine 2016e,

Alcolea, P.J., Alonso, A., Degayón, M.A., Moreno-Paz, M., Jiménez, M., Molina, R., Larraga, V. [2016]. In vitro infectivity and differential gene expression of Leishmania infantum metacyclic promastigotes: negative selection with peanut agglutinin in culture versus isolation from the stomodeal valve of Phlebotomus perniciosus.

Alcolea, P.J., Alonso, A., Domínguez, M., Parro, V., Jiménez, M., Molina, R., Larraga, V. [2016]. Influence of the microenvironment in the transcriptome of Leishmania infantum promastigotes: sand fly versus culture.

Fernández-Orgiler, A., Martínez, M., Alonso, A., Alcolea, P.J., Requena, J.M., Thomas, M.C., Blanco, L., Larraga, V. [2016]. A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage.

Alcolea, P.J., Alonso, A., García-Tabares, F., Mena, M.C., Ciordia, S., Larraga, V. [2016]. Proteome profiling of the growth phases of Leishmania pifanoi promastigotes in axenic culture reveals differential abundance of immunostimulatory proteins.

Alcolea, P.J., Alonso A., Moreno-Izquierdo, M.A., Degayón M.A., Moreno I., Larraga V. [2016]. Serum removal from culture induces growth arrest, ploidy alteration, decrease in infectivity and differential expression of crucial genes in Leishmania infantum promastigotes.

Alcolea PJ, Alonso A, García-Tabares F, Toraño A, Larraga V. [2014]. An Insight into the Proteome of Crithidia fasciculata Choanomastigotes as a Comparative Approach to Axenic Growth, Peanut Lectin Agglutination and Differentiation of Leishmania spp. Promastigotes.PLoS One. 2014 Dec 11;9(12):e113837. doi: 10.1371/journal

Alcolea PJ, Alonso A, Gómez MJ, Postigo M, Molina R, Jiménez M, Larraga V. [2014]. Stage-specific differential gene expression in Leishmania infantum: from the foregut of Phlebotomus perniciosus to the human phagocyte.BMC Genomics. 2014 Oct 3;15:849. doi: 10.1186/1471-2164-15-849.

Moreno MA, Alonso A, Alcolea PJ, Abramov A, de Lacoba MG, Abendroth J, Zhang S, Edwards T, Lorimer D, Myler PJ, Larraga V. [2014]. Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate.

Mejia E1, Burak M1, Alonso A2, Larraga V2, Kunkel TA3, Bebenek K4, Garcia-Diaz M5. [2014]. Structures of the Leishmania infantum polymerase beta.DNA Repair (Amst). 2014 Jun;18:1-9. doi: 10.1016/j.dnarep.2014.03.001. Epub 2014 Mar 22.

Moreno MA, Abramov A, Abendroth J, Alonso A, Zhang S, Alcolea PJ, Edwards T, Lorimer D, Myler PJ, Larraga V. [2014]. Structure of tyrosine aminotransferase from Leishmania infantum.Acta Crystallogr F Struct Biol Commun. 2014 May;70(Pt 5):583-7. doi: 10.1107/S2053230X14007845. Epub 2014 Apr 25.

San Martin-Uriz P, Mirete S, Alcolea PJ, Gomez MJ, Amils R, Gonzalez-Pastor JE. [2014]. Nickel-resistance determinants in Acidiphilium sp. PM identified by genome-wide functional screening.PLoS One. 2014 Apr 16;9(4):e95041. doi: 10.1371/journal.pone.0095041. eCollection 2014.

Alcolea PJ, Alonso A, Larraga V [2011]. Proteome profiling of Leishmania infantum promastigotes. The Journal of eukaryotic microbiology 2011, 58(4):352-358.

Alcolea PJ, Alonso A, Larraga V [2011]. Genome-wide gene expression profile induced by exposure to cadmium acetate in Leishmania infantum promastigotes.Int Microbiol. 2011 Mar;14(1):1-11.

Dujardin JC, Herrera S, do Rosario V, Arevalo J, Boelaert M, Carrasco HJ, Correa-Oliveira R, García L, Gotuzzo E, Gyorkos TW, Kalergis AM, Kouri G, Larraga V [2010]. Research priorities for neglected infectious diseases in Latin America and the Caribbean Region. PLoS Negl Trop Dis 4(10):e780

Alcolea PJ, Alonso A, Gómez MJ, Moreno I, Domínguez M, Parro V, Larraga V [2010]. Transcriptomics throughout the life cycle of Leishmania infantum: high down-regulation rate in the amastigote stage. Int J Parasitol 40:1497-516

Alcolea PJ, Alonso A, Gómez MJ, Sánchez-Gorostiaga A, Moreno-Paz M, González-Pastor E, Toraño A, Parro V, Larraga V [2010]. Temperature increase prevails over acidification in gene expression modulation of amastigote differentiation in Leishmania infantum. BMC Genomics 14, 11:31

Ramos I, Alonso A, Peris A, Marcen JM, Abengozar MA, Alcolea PJ, Castillo JA, Larraga V [2009]. Antibiotic resistance free plasmid DNA expressing LACK protein leads towards a protective Th1 response against Leishmania infantum infection. Vaccine 27(48):6695-703