Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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A. Gabba, A. Bogucka, J. G. Luz, A. Diniz, H. Coelho, F. Corzana, F. J. Cañada, F. Marcelo, P. V. Murphy & G. Birrane [2021]. Crystal structure of the carbohydrate recognition domain of the human macrophage galactose c-type lectin bound to galnac and the tumor-associated tn antigen. Biochemistry, 60, 17, 1327–1336. doi.org/10.1021/acs.biochem.1c00009

A. Puet, G. Dominguez, F. J. Cañada & J. Pérez-Castells [2021]. Synthesis and evaluation of novel iminosugars prepared from natural amino acids. Molecules, 26(2). doi: 10.3390/molecules26020394

A. Arda, U. Atxabal, S. Bertuzzi, A. Canales, F. J. Cañada, A. Gimeno, J. Ereño-Orbea, B. F. de Toro, A. Franconetti, M. Gómez-Redondo, M. G. Lete, M. P. Lenza, J. D. Martínez, M. J. Moure, A. Poveda, J. I. Quintana, P. Valverde, and J. Jiménez-Barbero [2021]. Recent advances in the application of NMR methodologies to analyze the conformation, dynamics, and interactions of saccharides. Carbohydrate Chemistry: Chemical and Biological Approaches Volume 44, pp 170-194. RSC. doi: 10.1039/9781788013864-00170

J. I. Quintana, S. Delgado, R. Núñez-Franco, F. J. Cañada, G. Jiménez-Osés, J. Jiménez-Barbero & A. Ardá [2021]. Galectin-4 n-terminal domain: Binding preferences toward a and b antigens with different peripheral core presentations. Frontiers in Chemistry, 9(193). doi: 10.3389/fchem.2021.664097.

H. Martin Merinero, M. Subías, A. Pereda, E. Gomez-Rubio, L. Juana-Lopez, C. Fernandez Rivera, E. Goicoechea De Jorge, S. Martin-Santamaria, F. J. Cañada & S. Rodríguez De Córdoba [2021]. The molecular bases for the association of fhr-1 with atypical hemolytic uremic syndrome and other diseases. Blood, 137 (25): 3484–3494. doi: 10.1182/blood.2020010069

M. C. Miller, Y. Zheng, D. Suylen, H. Ippel, F. J. Cañada, M. A. Berbis, J. Jimenez-Barbero, G.
Tai, H.-J. Gabius, and K. H. Mayo [2021]. Targeting the CRD F-face of Human Galectin-3 and Allosterically Modulating Glycan Binding by Angiostatic PTX008 and a Structurally Optimized Derivative. Chemmedchem. 16, 4, 713-723. doi: 10.1002/cmdc.202000742

F.J. Cañada, A. Canales, P. Valverde, B. Fernández de Toro, M. Martínez-Orts, P. Oquist-Phillips, A. Pereda [2021]. Conformational and Structural characterization of carbohydrates and their interactions studied by NMR. Curr Med Chem. doi: 10.2174/0929867328666210705154046

J. D. Martínez, A. I. Manzano, E. Calviño, A. d. Diego, B. Rodriguez de Francisco, C. Romanò, S. Oscarson, O. Millet, H.-J. Gabius, J. Jiménez-Barbero, and F. J. Cañada.
[2020]. Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by 19F NMR Spectroscopy. J. Org. Chem. 85, 16072-16081. doi: 10.1021/acs.joc.0c01830

Y. Shen, I. Kalograiaki, A. Prunotto, M. Dunne, S. Boulos, N. M. I. Taylor, E. T. Sumrall, M. R. Eugster, R. Martin, A. Julian-Rodero, B. Gerber, P. G. Leiman, M. Menéndez, M. D. Peraro, F. J. Cañada & M. J. Loessner [2021]. Structural basis for recognition of bacterial cell wall teichoic acid by pseudo-symmetric sh3b-like repeats of a viral peptidoglycan hydrolase. Chemical Science. 12, 2, 576-589 doi: 10.1039/D0SC04394J

J. A. Mendez-Liter, M. Nieto-Dominguez, B. F. De Toro, A. G. Santana, A. Prieto, J. L. Asensio, F. J. Cañada, L. I. De Eugenio & M. J. Martinez [2020]. A glucotolerant beta-glucosidase from the fungustalaromyces amestolkiaeand its conversion into a glycosynthase for glycosylation of phenolic compounds. Microb. Cell. Fact., 19(1). doi: 10.1186/s12934-020-01386-1

P. Valverde, J. D. Martínez, F. J. Cañada, A. Arda & J. Jiménez-Barbero [2020]. Molecular recognition in c-type lectins: The cases of dc-sign, langerin, mgl, and l-sectin. Chembiochem, 28. doi: 10.1002/cbic.202000238

A. G. Santana, L. Montalvillo-Jimenez, L. Diaz-Casado, F. Corzana, P. Merino, F. J. Cañada, G. Jiménez-Oses, J. Jiménez-Barbero, A. M. Gómez & J. L. Asensio [2020]. Dissecting the essential role of anomeric beta-triflates in glycosylation reactions. J. Am. Chem. Soc., 142(28), 12501-12514. doi: 10.1021/jacs.0c05525

M. Nieto-Domínguez, B. Fernández De Toro, L. I. De Eugenio, A. G. Santana, L. Bejarano-Muñoz, Z. Armstrong, J. A. Méndez-Líter, J. L. Asensio, A. Prieto, S. G. Withers, F. J. Cañada & M. J. Martínez [2020]. Thioglycoligase derived from fungal gh3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance. Nature Communications, 11(1), 4864. doi: 10.1038/s41467-020-18667-3

M. A. Pajares, T. Zimmermann, F. J. Sanchez-Gomez, A. Ariza, M. J. Torres, M. Blanca, F. J. Cañada, M. I. Montañez & D. Perez-Sala [2020]. Amoxicillin inactivation by thiol-catalyzed cyclization reduces protein haptenation and antibacterial potency. Front. Pharmacol., 11 doi: 10.3389/fphar.2020.00189

F. Queda, G. Covas, T. Silva, C. A. Santos, M. R. Bronze, F. J. Cañada, M. C. Corvo, S. R. Filipe & M. M. B. Marques [2019]. A top-down chemo-enzymatic approach towards n-acetylglucosamine-n-acetylmuramic oligosaccharides: Chitosan as a reliable template. Carbohydrate Polymers, 224-115133. doi.org/10.1016/j.carbpol.2019.115133

P. Valverde, S. Delgado, J. D. Martinez, J. B. Vendeville, J. Malassis, B. Linclau, N. C. Reichardt, F. J. Cañada, J. Jimenez-Barbero & A. Arda [2019]. Molecular insights into dc-sign binding to self-antigens: The interaction with the blood group a/b antigens. Acs Chemical Biology, 14(7), 1660-1671. doi: 10.1021/acschembio.9b00458

I. Gallego, A. Rioboo, J. J. Reina, B. Diaz, A. Canales, F. J. Cañada, J. Guerra-Varela, L. Sanchez & J. Montenegro [2019]. Glycosylated cell-penetrating peptides (gcpps). Chembiochem, 20(11), 1400-1409. doi: 10.1002/cbic.201800720

J. A. Méndez-Liter, I. Tundidor, M. Nieto-Dominguez, B. F. De Toro, A. G. Santana, L. I. De Eugenio, A. Prieto, J. L. Asensio, F. J. Cañada, C. Sanchez & M. J. Martinez [2019]. Transglycosylation products generated by talaromyces amestolkiae gh3 beta-glucosidases: Effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells. Microb. Cell. Fact., 18 doi: 10.1186/s12934-019-1147-4

J. D. Martinez, P. Valverde, S. Delgado, C. Romano, B. Linclau, N. C. Reichardt, S. Oscarson, A. Arda, J. Jimenez-Barbero & F. J. Cañada [2019]. Unraveling sugar binding modes to dc-sign by employing fluorinated carbohydrates. Molecules, 24(12). doi: 10.3390/molecules24122337

J. A. Valderrama, H. Gomez-Alvarez, Z. Martin-Moldes, M. A. Berbis, F. J. Cañada, G. Durante-Rodriguez & E. Diaz [2019]. A novel redox-sensing histidine kinase that controls carbon catabolite repression in azoarcus sp. Cib. mBio, 10(2). doi: 10.1128/mBio.00059-19