Publications | Centro de Investigaciones Biológicas Margarita Salas - CIB Margarita Salas

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Pesce, F., Diletta Stea, E., Divella, C., Accetturo, M., Laghetti, P., Gallo, P., Rossini, M., Cianciotta, F., Crispino, L., Granata, A., Battaglia, M., Lucarelli, G., Rodríguez de Córdoba, S., Stallone, G., Gesualdo, L. and Castellano, G. [2020]. DelCFHR3-1 influences graft survival in transplant patients with IgA nephropathy via complement mediated cellular senescence. Am. J. Transplant. doi: 10.1111/ajt.16350.

Caravaca-Fontán, F., Díaz-Encarnación, M.M., Lucientes, L., Cavero, T., Cabello, V., Ariceta, G., Quintana, L.F., Marco, H., Barros, X., Ramos, N., Rodríguez-Mendiola, N., Cruz, S., Fernández-Juárez, G., Rodríguez, A., José, A.P., Rabasco, C., Rodado, R., Fernández, L., Gómez, V.P., Ávila, A.I., Bravo, L., Lumbreras, J., Allende, N., Nieta, M.D.S.L., Rodríguez, E., Olea, T., Melgosa, M., Huerta, A., Miquel, R., Mon, C., Fraga, G., Lorenzo, A., Draibe, J., Cano-Megías, M., González, F., Shabaka, A., López-Rubio, M.E., Fenollosa, M.Á., Martín-Penagos, L., Silva, I.D., Titos, J.A., Córdoba, S.R., Jorge, E.G., Praga, M., Spanish Group for the Study of Glomerular Diseases GLOSEN [2020]. Mycophenolate mofetil in c3 glomerulopathy and pathogenic drivers of the disease. Clinical Journal of the American Society of Nephrology. 15:1287-1298.

Portoles, J., Huerta, A., Arjona, E., Gavela, E., Agúera, M., Jiménez, C., Cavero, T. Marrero, D., Rodríguez de Córdoba, S., Diekmann, F., on behalf of MATRIX investigators. [2020]. Characteristics, management and outcomes of atypical haemolytic uremic syndrome in kidney transplant patients: a retrospective national study. Clin. Kid. J. doi.org/10.1093/ckj/sfaa096

Arjona, E., Huerta, A., Goicoechea de Jorge, E., Rodríguez de Córdoba, S. [2020]. The familial risk of developing atypical Hemolytic Uremic Syndrome. Blood. 136:1558-1561

Lumbreras, J., Subias, M., Espinosa, N., Ferrer, J.M., Arjona, E., Rodríguez de Córdoba, S. [2020]. The Relevance of the MCP Risk Polymorphism to the Outcome of aHUS Associated With C3 Mutations. A Case Report. Frontiers in Immunology. doi: 10.3389/fimmu.2020.01348

Martínez-López, D., Roldan-Montero, R., García-Marqués, F., Nuñez, E., Jorge, I., Camafeita, E., Minguez, P., Rodriguez de Cordoba, S., López-Melgar, B., Lara-Pezzi, E., Fernández-Ortiz, A., Ibáñez, B., Valdivielso, J.M., Fuster, V., Michel, J.-B., Blanco-Colio, L.M., Vázquez, J., Martin-Ventura, J.L. [2020]. Complement C5 Protein as a Marker of Subclinical Atherosclerosis. Journal of the American College of Cardiology. 75:1926-1941.

Urban, A., Volokhina, E., Felber, A., Stasitojc, G., Blom, AM., Jongerius, I., Van den Heuvel, L., Thiel, M., Oldziej, S., Arjona, E., Rodríguez de Córdoba, S. and Okrój, M. [2020]. Gain-of-function mutation in complement C2 protein identified in patient with atypical hemolytic uremic syndrome (aHUS) J. Allergy Clin. Immunol. 146:916-919.e11

Cavero, T., Arjona, E., Soto, K., Caravaca, F., Rabasco, C., Bravo, L., De la Cerda, F., Martín, N., Blasco, M., Avila, A., Huerta, A., Cabello-Chávez, V., Jarque, A., Alcázar, C., Fulladosa, X., Carbayo, J., Anaya, S., Cobelo, C., Ramos, N., Iglesias Lamas, E., Baltar, J., Martínez-Gallardo, R., Pérez-Tamajón, L., Morales, E., González, R., Macía, M., Draibe, J., Pallardo, L., Quintana, L., Espinosa, M., Barros, X., Pereira, F., Cao, M., Moreno, JA., Rodríguez de Córdoba, S., Praga, M., and Spanish Group for the Study of Glomerular Diseases (GLOSEN) [2019]. Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome. Kidney Int. 96:995-1004

Luque, A., Serrano, I., Ripoll, E., Malta, C., Gomà, M., Blom, AM., Grinyó, JM., Rodríguez de Córdoba, S., Torras, J., and Aran, JM. [2020]. Noncanonical immunomodulatory activity of complement regulator C4BP(β-) limits the development of lupus nephritis. Kidney Int. 97:551-566

Jager, NM., Van Zanden, JE., Subías, M., Leuvenink, HGD., Daha, MR., Rodríguez de Córdoba, S., Poppelaars, F. and Seelen, MA. [2019]. Blocking complement factor B activation reduces renal injury and inflammation in a rat brain death model. Frontiers in Immunology doi:10.3389/fimmu.2019.02528.

Rodríguez de Córdoba, S., Espinosa Hernández, M. [2019]. Kidney, hypertension and complement activation. In search of new therapeutic targets . Nefrologia. 39:111-114.

Gómez, S., Querol-García, J., Sánchez-Barrón, G., Subias, M., González-Alsina, À., Franco-Hidalgo, V., Albertí, S., De Córdoba, S.R., Fernández, F.J., Vega, M.C. [2019]. The antimicrobials anacardic acid and curcumin are not-competitive inhibitors of Gram-positive bacterial pathogenic glyceraldehyde-3-phosphate dehydrogenase by a mechanism unrelated to human C5A anaphylatoxin binding. Frontiers in Microbiology. 10:-.

Praga, M., Rodríguez de Córdoba, S. [2019]. Secondary atypical hemolytic uremic syndromes in the era of complement blockade. Kidney International. 95:1298-1300.

Smith, R.J.H., Appel, G.B., Blom, A.M., Cook, H.T., D’Agati, V.D., Fakhouri, F., Fremeaux-Bacchi, V., Józsi, M., Kavanagh, D., Lambris, J.D., Noris, M., Pickering, M.C., Remuzzi, G., de Córdoba, S.R., Sethi, S., Van der Vlag, J., Zipfel, P.F., Nester, C.M. [2019]. C3 glomerulopathy — understanding a rare complement-driven renal disease. Nature Reviews Nephrology. :-.

Cao, M., Leite, B.N., Ferreiro, T., Calvo, M., Fernández, C., Alonso, Á., Rodriguez, A., Salvador, P., Seijo, R., Pita, S., Arjona, E., Rodríguez De Córdoba, S., Valdés Cañedo, F. [2018]. Eculizumab modifies outcomes in adults with atypical hemolytic uremic syndrome with acute kidney injury. American Journal of Nephrology. 48:225-233.

Goicoechea de Jorge, E., López Lera, A., Bayarri-Olmos, R., Yebenes, H., Lopez-Trascasa, M., Rodríguez de Córdoba, S. [2018]. Common and rare genetic variants of complement components in human disease. Molecular Immunology. 102:42-57.

Pouw, R.B., Delgado, I.G., Lera, A.L., de Córdoba, S.R., Wouters, D., Kuijpers, T.W., Sánchez-Corral, P. [2018]. High complement factor H-related (FHR)-3 levels are associated with the atypical hemolytic-uremic syndrome-risk allele CFHR3*B. Frontiers in Immunology. 9:848.

Osborne, A.J., Breno, M., Borsa, N.G., Bu, F., Fremeaux-Bacchi, V., Gale, D.P., Van Den Heuvel, L.P., Kavanagh, D., Noris, M., Pinto, S., Rallapalli, P.M., Remuzzi, G., De Cordoba, S.R., Ruiz, A., Smith, R.J.H., Vieira-Martins, P., Volokhina, E., Wilson, V., Goodship, T.H.J., Perkins, S.J. [2018]. Statistical validation of rare complement variants provides insights into the molecular basis of atypical hemolytic uremic syndrome and C3 glomerulopathy. Journal of Immunology. 200:2464-2478.

Boshra H, Zelek WM, Hughes TR, Rodríguez de Córdoba S and Morgan P. [2018]. Absence of CD59 in Guinea Pigs: Analysis of the Cavia Porcellus genome suggests the evolution of a CD59 pseudogene. J Immunol. 200:327-335.

Jiménez-Reinoso A., Marín AV., Subías M., López-Lera A., Román-Ortíz E., Payne K., Ma CS., Arbore G., Kolev M., Freeley SJ., Kemper C., Tangye SG., Fernández-Malavé E., Rodríguez de Córdoba S., López-Trascasa M. and Regueiro JR. [2017]. Human plasma C3 is essential for the development of memory B, but not T, lymphocytes. J Allergy Clin Immunol. 141:1151-1154.